October 1, 1995Clinical Otolaryngology

Do patients with epistaxis have drug-induced platelet dysfunction?

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Why the study?

Is NSAID intake and associated platelet dysfunction correlated with epistaxis?

Population

50 patients with epistaxis and 50 controls

Comparison

NSAID intake vs Controls without epistaxis

Design

Case-control

Authors

JLJonathan R. LiveseyYork Hospital MWMelanie Watson PKPamela J. Kelly

Discussion

Member takes

Implication

NSAID history and platelet testing may inform epistaxis evaluation; hypothesis-generating for causality and practice change.

Structured PICO

Is NSAID intake and associated platelet dysfunction correlated with epistaxis?

Population

50 patients with epistaxis and 50 controls

Intervention

NSAID intake

Comparator

Controls without epistaxis

Outcome

NSAID intake and platelet function (platelet response to collagen and arachidonic acid aggregation and adenosine triphosphate release)surrogate

NSAID-induced platelet dysfunction and hypertension are significantly associated with epistaxis and should be considered in its multifactorial etiology.

Cite This Study

Livesey et al. (1995) studied this question.

synapsesocial.com/papers/6a70d7722163a0a01bc50bb7 https://doi.org/10.1111/j.1365-2273.1995.tb00071.x

Topics

Dual antiplatelet therapy Hypertension management

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Ask AI

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Do patients with epistaxis have drug-induced platelet dysfunction?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Do patients with epistaxis have drug-induced platelet dysfunction?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider