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April 1, 1995Journal of Clinical InvestigationOpen Access

An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.

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Authors

PNPaquita NurdenPSPierre SaviEHE Heilmann

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Cite This Study

Nurden et al. (1995) studied this question.

synapsesocial.com/papers/6a70d7d9f44fa9f079de90d5https://doi.org/10.1172/jci117835
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Two mechanisms for inhibition of ADP-induced platelet shape change by 5'-p-fluorosulfonylbenzoyladenosine. Conversion to adenosine, and covalent modification at an ADP binding site distinct from that which inhibits adenylate cyclase.1985 · 45 citations
  2. 2A receptor-induced binding site in fibrinogen elicited by its interaction with platelet membrane glycoprotein IIb-IIIa1991 · 77 citations
  3. 3Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.1985 · 963 citations
  4. 4Glanzmann's thrombasthenia: the spectrum of clinical disease1990 · 639 citations
  5. 5Thrombin induces a rapid redistribution of glycoprotein Ib-IX complexes within the membrane systems of activated human platelets1990 · 149 citations