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October 1, 1994Journal of Biological ChemistryOpen Access

Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets.

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Authors

SJShaun P. JacksonCross-Cutting CardiologySSSimone M. SchoenwaelderThe University of SydneyYYYuping YuanThe University of Sydney

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Jackson et al. (1994) studied this question.

synapsesocial.com/papers/6a70da653ce530166bc2f21fhttps://doi.org/10.1016/s0021-9258(18)47130-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Activated phosphoinositide 3-kinase associates with membrane skeleton in thrombin-exposed platelets.1992 · 184 citations
  2. 2Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.1985 · 963 citations
  3. 3Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor.1992 · 323 citations
  4. 4Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts1994 · 133 citations
  5. 5Phosphoinositide kinases1990 · 332 citations