Why the study?
Does epicardial fat tissue thickness measured by echocardiography accurately predict metabolic syndrome in geriatric patients?
Does epicardial fat tissue thickness measured by echocardiography accurately predict metabolic syndrome in geriatric patients?
Epicardial fat tissue thickness >7.3 mm measured by echocardiography is a highly sensitive and specific diagnostic criterion for metabolic syndrome in geriatric patients.
EFTT may aid MetS diagnosis in geriatrics; leaves open validation before clinical adoption.
OBJECTIVE: To evaluate the epicardial fat tissue thickness (EFTT) as a diagnostic criterion for geriatric patients with metabolic syndrome (MetS). METHODS: Sixty geriatric patients over 65 years of age were recruited for the study. Patients were divided into two groups: Group 1 (n = 30) consisted of patients with MetS; Group 2 (n = 30) consisted of patients without MetS. Echocardiography was used to measure EFTT in all patients, and blood samples were analyzed for biochemical parameters. RESULTS: Compared to Group 2, EFTT levels of Group 1 were statistically higher (P < 0.05). In a binary logistic regression analysis, EFTT levels served as the independent factor for metabolic syndrome (B = 17.35, SE = 4.93, Wald = 12.36, P < 0.001). Receivers operating characteristic Curve (ROC-curve) analysis revealed that EFTT predicted MetS with 96.7% sensitivity and 86.7% specificity above the level of 7.3 mm [area under the curve = 0.969; 95% confidence interval (CI): 0.928-1.00]. CONCLUSIONS: The present study demonstrated that serum EFTT levels were higher in geriatric patients with MetS and can therefore be used as a diagnostic criterion for MetS.
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Kaya et al. (2015) studied this question.
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