Noninvasive Phenotypes of Atherosclerosis
Population
1,821 patients from a Premature Atherosclerosis Clinic
Design
Cross-sectional
Authors
Discussion
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Member takes
Overview
Supports viewing plaque area and stenosis as distinct phenotypes; leaves open differential utility in stroke risk models.
Structured PICO
P
Population
1,821 patients from a Premature Atherosclerosis Clinic
O
Outcome
Total carotid plaque area and carotid stenosis as measured by ultrasoundsurrogate
Total carotid plaque area and carotid stenosis represent distinct phenotypes of atherosclerosis with different risk factor associations, highlighting the need to distinguish between them in future studies.
Cite This Study
Spence et al. (2004) studied this question.