Key result
Childhood cardiovascular risk factors significantly tracked into young adulthood, with children in the highest quartile for total cholesterol at age 8 having a 4.19-fold increased risk of remaining in the highest quartile at age 21.
Population
477 individuals born in KEM Hospital, Pune, India in 1987-1989, with 357 participating at 21 years of age.
Design
Cohort
Follow-up
13 years
Authors
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Supports early risk stratification in children; extends tracking data to LMICs but remains hypothesis-generating.
Cohort (n=357)
No
Relative Risk: 4.19 (95% CI 2.94–5.97)
p-value: p=<0.001
Cardiovascular risk factors, particularly adiposity and cholesterol, show significant tracking from childhood to young adulthood in a low- and middle-income country, highlighting the need for early public health interventions.
Joshi et al. (2014) conducted a cohort in Cardiovascular risk factors (n=357). Highest quartile of total cholesterol at age 8 vs. Lower quartiles of total cholesterol at age 8 was evaluated on Persistence in the highest quartile of total cholesterol at age 21 (RR 4.19, 95% CI 2.94, 5.97, p=<0.001). Childhood cardiovascular risk factors significantly tracked into young adulthood, with children in the highest quartile for total cholesterol at age 8 having a 4.19-fold increased risk of remaining in the highest quartile at age 21.
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