Animal study demonstrates that running combined with energy restriction degrades bone structure but preserves muscle adaptation in young female rats, indicating divergent tissue responses to low...
Low energy availability impairs bone parameters but may assist muscle adaptation from endurance training. Our study demonstrated that the combination of running and energy restriction (ER) impaired bone mineral density and bone microarchitecture in young female rats. However, running increased the cross-sectional area of type I and IIA fibers, and the levels of mitochondrial proteins in plantaris muscle under both ad libitum feeding and ER conditions in young female rats.
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Aikawa et al. (2025) studied this question.
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