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November 1, 2023Orthopaedic Journal of Sports MedicineOpen Access

Effects of a Perioperative Blood Flow Restriction Therapy Program on Early Quadriceps Strength and Patient-Reported Outcomes After Anterior Cruciate Ligament Reconstruction

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Why the study?

Quadriceps muscle atrophy remains a limiting factor in returning to activity after ACLR, and blood flow restriction therapy may accelerate quadriceps strengthening perioperatively.

Does a perioperative blood flow restriction therapy program improve early quadriceps strength in patients undergoing anterior cruciate ligament reconstruction?

Population

46 patients indicated for ACLR

Comparison

Perioperative blood flow restriction therapy vs control

Design

Randomized controlled trial

Follow-up

6 months

Authors

KOKelechi R. OkorohaJTJoseph S. TramerLKLafi S. Khalil

Discussion

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Overview

Perioperative BFR improves early quadriceps strength and PROs after ACLR; extends evidence for short-term use in rehabilitation.

Structured PICO

Does a perioperative blood flow restriction therapy program improve early quadriceps strength in patients undergoing anterior cruciate ligament reconstruction?

P
Population
46 patients indicated for anterior cruciate ligament reconstruction (ACLR) (mean age 25.4 in BFR group, 27.5 in control group).
I
Intervention
Perioperative blood flow restriction (BFR) therapy program including 2 weeks prehabilitation and 12-week postoperative physical therapy using a pneumatic cuff set to 80% limb occlusion pressure.
C
Comparator
Standardized 2 weeks prehabilitation and 12-week postoperative physical therapy protocol without BFR.
O
Outcome
Postoperative isometric quadriceps strength (peak and mean torque during seated leg extension, presented as quadriceps index).surrogate

Integrating blood flow restriction into perioperative physical therapy protocols improves early (6-week) quadriceps strength and patient-reported outcomes after ACL reconstruction, though differences do not persist at 3 and 6 months.

Cite This Study

Okoroha et al. (2023) studied this question.

synapsesocial.com/papers/6a70df07e71d69abee08e9dehttps://doi.org/10.1177/23259671231209694
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Poster 233: The Effect of Early Blood Flow Restriction Training on Quadriceps Muscle Strength and Functional Performance Following Isolated Anterior Cruciate Ligament Reconstruction: A Double-Blind Randomized Controlled Trial2025
  2. 2The Effect of Blood Flow Restriction Training on Quadriceps Muscle Strength and Functional Performance Following Isolated Anterior Cruciate Ligament Reconstruction: A Pilot Study2025 · 2 citations
  3. 3Paper 21: Blood Flow Restriction Therapy Improves Early Patient Reported Outcomes Following ACL Reconstruction2022 · 4 citations
  4. 4Blood Flow Restriction Therapy for 2 Weeks Prior to Anterior Cruciate Ligament Reconstruction Did Not Impact Quadriceps Strength Compared to Standard Therapy2022 · 22 citations
  5. 5Effect of quadriceps training at different levels of blood flow restriction on quadriceps strength and thickness in the mid-term postoperative period after anterior cruciate ligament reconstruction: a randomized controlled external pilot study2023 · 42 citations