Why the study?
Does CHRM2 gene polymorphism affect heart rate recovery after maximal exercise before and after endurance training in healthy sedentary individuals?
Population
95 sedentary men and women, mean age 42 +/- 5 yr
Comparison
2-wk laboratory-controlled endurance training… vs Control group (no endurance training)
Design
Cohort
Follow-up
2 weeks
Authors
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C/C homozygotes showed lower HR recovery; leaves open CHRM2 rs324640 as modifier of autonomic recovery pending replication.
Does CHRM2 gene polymorphism affect heart rate recovery after maximal exercise before and after endurance training in healthy sedentary individuals?
DNA sequence variation at the CHRM2 locus is a potential modifier of heart rate recovery in the sedentary state and after short-term endurance training in healthy individuals.
Hautala et al. (2006) studied this question.
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