Why the study?
Does administration of a converting-enzyme inhibitor improve the diagnostic accuracy of renal-vein plasma renin activity ratios for detecting unilateral renal disease in hypertensive patients?
Population
14 unselected hypertensive patients undergoing bilateral renal-vein catheterization
Comparison
Nonapeptide converting-enzyme inhibitor 0.25 mg… vs Pre-treatment baseline (before CEI administration)
Design
Cohort
Authors
Loading...
Supports adjunctive CEI during renal-vein sampling to increase PRA lateralization; leaves open prospective validation of diagnostic accuracy.
Does administration of a converting-enzyme inhibitor improve the diagnostic accuracy of renal-vein plasma renin activity ratios for detecting unilateral renal disease in hypertensive patients?
Administration of a converting-enzyme inhibitor during renal-vein catheterization significantly increases the lateralization of plasma renin activity in patients with unilateral renal disease, improving diagnostic accuracy.
Ré et al. (1978) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: