Why the study?
Receptor usage is an important determinant of diseases induced by pathogenic retroviruses, with distinct receptor recognition associated with different feline diseases.
Key points are not available for this paper at this time.
Receptor-defined FeLV subgroups may refine feline disease prediction; leaves open translation to human retroviral therapies.
Receptor usage is an important determinant of diseases induced by pathogenic retroviruses. In the case of feline leukemia viruses, three subgroups (A, B, and C) based on their ability to recognize different cell host receptors, respectively, the thiamine transporter THTR1, the phosphate transporter PiT1, and the heme exporter FLVCR1, are associated with distinct feline diseases.
No takes yet. Share an insight, caveat, or question.
Tury et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: