Randomized trial reports on high-flow conditioned oxygen therapy for extubation failure in high-risk critically ill patients, highlighting the need to evaluate safety against noninvasive ventilation.
Critically ill mechanically ventilated patients are usually stratified in two levels according to the risk for reintubation. In low-risk patients high flow conditioned oxygen therapy (HFO) may reduce reintubation, whereas in high-risk patients non-invasive mechanical ventilation (NIMV) to prevent reintubation is gaining acceptance. However, data on the efficacy or safety of HFO in high-risk patients are lacking.
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Hernández et al. (2015) studied this question.
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