Chemical ionization desorption mass spectrometry as an additional tool for the structure elucidation of nucleosides

Promising results were obtained by chemical ionization desorption mass spectrometry for a series of original pyridinium nucleoside salts, together with some purine and pyrimidine nucleo(t)sides. They were recorded using ammonia as reagent gas and tungsten wires. Principal ions correspond to protonated or cationized ([NH4]+) forms of the molecular ion or the free base depending upon the compound under investigation.