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While largely replaced by stents and modern pharmacotherapy, autoperfusion balloons may still hold value in specific complex anatomical scenarios and emerging therapies requiring prolonged inflation.
The development of the autoperfusion balloon catheter provided the ability to perform prolonged balloon inflations during angioplasty procedures. For a number of years the autoperfusion balloon catheter was successfully used to treat acute complications of percutaneous coronary interventions. However, with the advent of stent implantation procedures and the use of platelet glycoprotein IIb/IIIa receptor inhibitors, the role of autoperfusion balloon angioplasty has decreased. However, the perfusion balloon may have an important role in angioplasty and/or stenting of coronary lesions with unfavorable coronary anatomy and also in carotid angioplasty. The perfusion balloon also may be helpful for the treatment of in‐stent restenosis. In the future the autoperfusion balloon or its principle may hold promise in emerging interventions, such as gene therapy and vascular brachytherapy where prolonged interrupted of coronary circulation is required.
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Kipshidze et al. (1999) studied this question.
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