Why the study?
Chronic cardiomyopathy is the most frequent presentation of Chagas disease and leads to adverse cardiac outcomes, warranting effective noninvasive methods like CMR to assess myocardial damage and risk markers.
Cardiovascular magnetic resonance imaging is a highly reliable noninvasive method for morphofunctional analysis and identifying risk markers in patients with Chagas disease.
CMR aids Chagas cardiomyopathy evaluation and risk stratification; leaves open routine adoption without prospective outcome data.
Chagas disease represents an important public health problem, especially in endemic countries in Latin America. Chronic cardiomyopathy is its most frequent clinical presentation. Myocardial involvement has a multifactorial pathogenesis and can lead to heart failure, thromboembolic events, arrhythmias, and sudden death. In this context, cardiovascular magnetic resonance imaging (CMR) is an excellent noninvasive method for investigating myocardial damage and understanding the mechanisms and consequences of these injuries. CMR has high spatial resolution and tissue characterization capacity, enabling a highly reliable morphofunctional analysis and the identification of risk markers for adverse events in patients with Chagas disease. This exam is very useful for the diagnosis and follow-up of these patients in the routine clinical setting.
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Moreira et al. (2022) studied this question.
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