Answers are grounded in this paper and cite their sources.
This article reviews four 'DNA screening techniques', namely heteroduplex analysis, single-strand conformational polymorphism (SSCP), denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) as tools for the study of allelic variation in natural populations. The resolving power, advantages, and limitations of each technique are discussed and compared. We also provide some criteria for choosing among techniques and illustrate some practical issues with examples taken primarily from our own laboratory experience.
No takes yet. Share an insight, caveat, or question.
Lessa et al. (1993) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: