Why the study?
Does the use of SSRIs or TCAs increase the risk of nonvertebral fractures in individuals aged 55 years and older?
Does the use of SSRIs or TCAs increase the risk of nonvertebral fractures in individuals aged 55 years and older?
In elderly individuals, the use of SSRIs and TCAs is associated with a significantly increased risk of nonvertebral fractures, which worsens with prolonged SSRI use.
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SSRI use was associated with higher nonvertebral fracture risk in adults ≥55; leaves open confounding versus causality and warrants prospective confirmation.
Ziere et al. (2008) studied this question.
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