Why the study?
Does migraine increase the risk of adverse pregnancy outcomes or congenital malformations in pregnant women?
Does migraine increase the risk of adverse pregnancy outcomes or congenital malformations in pregnant women?
Migraine and its commonly used treatments do not appear to increase the risk of adverse pregnancy outcomes or congenital malformations.
Similar rates observed; observational data leaves open effects of migraine subtypes or therapies.
The reproductive histories of 777 women suffering from migraine were compared with 182 non-migrainous women. The incidence of miscarriage, stillbirth and toxaemia of pregnancy was very similar in both groups and there was no increase in the number of congenital malformations in the children born to women who suffered from migraine compared with the control group or with the national average. It was concluded that women suffering from migraine did not have an increased risk of giving birth to children with deformity and it was unlikely that drugs most commonly used in the treatment of migraine were teratogenic.
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Wainscott et al. (1978) studied this question.
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