February 7, 2012Nursing in Critical Care

The use of propofol sedation in a paediatric intensive care unit

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Why the study?

Is continuous intravenous propofol sedation safe and free of propofol infusion syndrome in children admitted to the PICU?

Population

174 children younger than 16 years admitted to a paediatric intensive care unit at a University Hospital who…

Design

Cohort

Follow-up

within 6 h after completion of the propofol infusion

Authors

MSMarie‐Louise SvenssonBoston Children's Hospital LLLars LindbergLund University

Discussion

Member takes

Implication

Supports safe propofol sedation in PICU children; leaves open randomized confirmation that safety is independent of dose or duration.

Structured PICO

Is continuous intravenous propofol sedation safe and free of propofol infusion syndrome in children admitted to the PICU?

Population

174 children younger than 16 years admitted to a paediatric intensive care unit (PICU) at a University Hospital who received propofol infusion, median age 2 years 10 months.

Intervention

Continuous intravenous propofol sedation (median dose 2.9 mg/kg/h, median duration 13 h)

Outcome

Occurrence of propofol infusion syndrome (PRIS), metabolic derangements, or circulatory failuresafety

Continuous intravenous propofol sedation was used safely in a PICU population with no occurrences of propofol infusion syndrome, suggesting adverse effects may not be directly related to dose or duration.

Cite This Study

Svensson et al. (2012) studied this question.

synapsesocial.com/papers/6a70f1d9f44fa9f079deb17e https://doi.org/10.1111/j.1478-5153.2012.00488.x

View Full Paper

Ask AI

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The use of propofol sedation in a paediatric intensive care unit

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The use of propofol sedation in a paediatric intensive care unit

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider