Clinical characteristics and initial management of patients with tuberculous pericarditis in the HIV era: the Investigation of the Management of Pericarditis in Africa (IMPI Africa) registry
Why the study?
Does HIV co-infection alter the clinical presentation and management of patients with suspected tuberculous pericarditis?
Population
185 adult patients with suspected tuberculous pericarditis recruited from 15 hospitals in three countries in…
Comparison
HIV co-infection vs No HIV co-infection
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May warrant closer monitoring in HIV co-infection; leaves open whether management should change pending prospective data.
Structured PICO
Does HIV co-infection alter the clinical presentation and management of patients with suspected tuberculous pericarditis?
P
Population
185 adult patients with suspected tuberculous pericarditis recruited from 15 hospitals in three countries in sub-Saharan Africa.
I
Intervention
HIV co-infection
C
Comparator
No HIV co-infection
O
Outcome
Differences in clinical presentation, diagnostic evaluation, and treatment based on HIV status
HIV co-infection in patients with tuberculous pericarditis is associated with more severe clinical presentations, including myopericarditis and haemodynamic instability, suggesting a need for more intensive cardiac management.
Cite This Study
Mayosi et al. (2006) studied this question.