Why the study?
Does intrapericardial urokinase along with conventional treatment prevent pericardial constriction in patients with infectious exudative pericarditis?
Population
94 patients with infectious exudative pericarditis, mean age 45.4 ± 14.7 years, 44 males and 50 females.
Comparison
Intrapericardial urokinase along with… vs Conventional treatment alone.
Design
RCT, Randomly given
Follow-up
mean 56.8 ± 29.0 months (range 8 to 120 months)
Authors
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Supports adding intrapericardial urokinase to standard care for infectious exudative pericarditis; extends RCT evidence for preventing constriction.
Does intrapericardial urokinase along with conventional treatment prevent pericardial constriction in patients with infectious exudative pericarditis?
Intrapericardial urokinase irrigation significantly reduces the risk of developing pericardial constriction in patients with infectious exudative pericarditis.
Han-binCui et al. (2005) studied this question.
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