Why the study?
Although DOACs are recommended for cancer-associated venous thromboembolism, firm evidence regarding their efficacy and safety in patients with urologic cancer was lacking.
Does rivaroxaban reduce the composite event of clinically relevant bleeding or VTE recurrence in patients with urologic cancer-associated VTE compared to dalteparin?
Population
124 eligible VTE patients with urologic cancers
Comparison
Rivaroxaban vs dalteparin
Design
Retrospective medical record review
Authors
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Rivaroxaban may be considered for urologic cancer VTE; leaves open need for randomized confirmation in this population.
Does rivaroxaban reduce the composite event of clinically relevant bleeding or VTE recurrence in patients with urologic cancer-associated VTE compared to dalteparin?
Rivaroxaban showed comparable efficacy and safety to dalteparin for treating cancer-associated VTE in patients with urologic cancer, supporting its use as a viable alternative.
Lee et al. (2019) studied this question.
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