Why the study?
Does HPLC-MS/MS provide a precise and reliable method for measuring aldosterone in human plasma compared to immunoassay?
Population
Human plasma and serum samples, including blood collected midmorning from 97 normotensive seated subjects…
Comparison
Online high-performance liquid… vs Immunoassay
Design
Other
Authors
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May offer precise aldosterone measurement by HPLC-MS/MS; leaves open clinical outcome validation versus immunoassay.
Does HPLC-MS/MS provide a precise and reliable method for measuring aldosterone in human plasma compared to immunoassay?
The online HPLC-MS/MS method provides a precise, high-throughput, and semiautomated approach for measuring aldosterone across the clinically relevant range, offering a reliable alternative to immunoassay.
Taylor et al. (2009) studied this question.
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