Key result
Intravenous heparin resolves straddling patent foramen ovale thrombus and neurologic deficits in ischemic stroke.
Case Report (n=1)
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Paradoxical embolism is a well-recognized cause of stroke. While the diagnosis in the majority of the cases with a patent foramen ovale is presumptive, numerous treatment strategies have been described. However, there is no single approach that has been overwhelmingly recommended for these patients. A patient is described who presented with ischemic stroke. Transesophageal echocardiography revealed a thrombus that straddled a patent foramen ovale. Anticoagulation with intravenous heparin resulted in resolution of thrombus and neurologic deficit. The literature regarding diagnosis and treatment of paradoxical embolism in the presence of patent foramen ovale is reviewed.
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Rachko et al. (2001) conducted a case report in Ischemic stroke and paradoxical embolism with a thrombus straddling a patent foramen ovale (n=1). Anticoagulation with intravenous heparin was evaluated on Resolution of thrombus and neurologic deficit. Anticoagulation with intravenous heparin resolved both the straddling patent foramen ovale thrombus and neurologic deficit in 1 patient with ischemic stroke.
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