November 1, 1987The Journal of Cell BiologyOpen Access

Rigor crossbridges are double-headed in fast muscle from crayfish.

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Structured PICO

Population

Fast muscle fibers from glycerol-extracted abdominal flexor muscle of crayfish

Intervention

Dissociation of the backbone of myosin filaments in 0.6 M KCl to obtain natively decorated thin filaments, followed by freeze-fracture, deep-etching, rotary shadowing, and negative staining

Comparator

Intact fibers

Outcome

Structure of rigor crossbridges (shape, spacing, and disposition)surrogate

Rigor crossbridges in crayfish fast muscle are double-headed and maintain their structural integrity and original spacing even when isolated.

Discussion

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Implication

Does not inform cardiac therapeutics; leaves open whether double-headed rigor crossbridges generalize to mammalian myocardium.

Cite This Study

Bard et al. (1987) studied this question.

synapsesocial.com/papers/6a70fcaf660549caf2c5a05a https://doi.org/10.1083/jcb.105.5.2225

View Full Paper

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Bookmark

Rigor crossbridges are double-headed in fast muscle from crayfish.

Structured PICO

Discussion

Implication

Cite This Study

Rigor crossbridges are double-headed in fast muscle from crayfish.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider