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March 25, 2019Annual Review of Food Science and Technology

Advances in Infant Formula Science

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Authors

GAGrace AhernAHAlan A. HennessyCRC. Anthony Ryan

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Overview

Review reveals advancements in formulating bioactive infant milk to guide neonatal development, suggesting enhanced microbiome programming and infection protection.

Key Points

  • To review recent scientific advancements in infant milk formula design, emphasizing bioactive components that mimic the functional properties of human milk.
  • Narrative synthesis of recent evidence regarding the bioactive and nutritional composition of human milk.
  • Evaluation of industrial advances integrating specialized proteins, fatty acids, and complex carbohydrates into formula products to modulate the neonatal microbiome.
  • Identified functional additions to infant formulas, including specialized protein fractions and complex carbohydrates, that mechanistically emulate human milk's protective effects against infection.
  • Highlighted infant milk formula as a primary dietary intervention capable of guiding neonatal microbiota assembly via prebiotics, probiotics, and synbiotics to influence long-term health.

Cite This Study

Ahern et al. (2019) studied this question.

synapsesocial.com/papers/6a70fd3be71d69abee08fa56https://doi.org/10.1146/annurev-food-081318-104308
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Also Consider

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  1. 1Supporting the Growing Infant: From Human Milk to Specialized Infant Formulas2025
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  4. 4FDA Expert Panel on Infant Formula “Operation Stork Speed” June 2025: Part 3, Marketing of Infant Formulas, Breastfeeding Support, Hypoallergenic Formulas, and Nutrition for Preterm Infants2025
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