Answers are grounded in this paper and cite their sources.
In the present study, methanolic extract of tuber of Stephania glabra was evaluated for H1-bloker activity by employing in vitro screening models of guinea pig ileum and goat tracheal chain preparation. Goat isolated trachea and guinea pig ileum contracted to histamine in a dose-dependent manner while chlorpheniramine blocked this effect. The methanolic extract produced significant dose-dependent H1-receptor antagonist activity by blocking histamine-induced contraction.
No takes yet. Share an insight, caveat, or question.
Khan et al. (2010) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: