Key result
Older age at balloon angioplasty for recurrent coarctation is linked to ~6% higher reintervention risk.
Why the study?
The long-term efficacy, safety, and outcomes of balloon angioplasty for recurrent aortic coarctation without stents were not well established.
Does percutaneous balloon angioplasty without stents improve long-term outcomes in patients with recurrent aortic coarctation?
Cohort (n=99)
Does percutaneous balloon angioplasty without stents improve long-term outcomes in patients with recurrent aortic coarctation?
Percutaneous balloon angioplasty for recurrent aortic coarctation is safe and effective long-term, though older age at intervention is associated with a higher risk of reintervention.
Answers are grounded in this paper and cite their sources.
Long-term survival after balloon angioplasty for recurrent coarctation appears favorable despite age-related reintervention risk; leaves open prospective comparisons to stenting.
AIMS: To assess the efficacy, safety, and long-term results of the balloon angioplasty of recoarctation. METHODS AND RESULTS: The angioplasty was performed in 99 consecutive patients aged 36 days to 32.6 years (median 268 days). Recoarctation to descending aorta diameter ratio increased from 0.44 (0.35/0.50) to 0.66 (0.57/0.77), P < 0.001. Systolic gradient was reduced from 34.0 (26.0/44.75) to 15.0 (8.25/27.0) mmHg, P < 0.001. In seven patients (7.1%) the procedure was ineffective. One patient (1%) with heart failure died within 24 h after a successful angioplasty and in another (1%) an intimal abruption necessitated surgical revision. The follow-up ranged up to 20.7 years (median 8.1 years). Actuarial probability of survival 20.7 years after the procedure was 0.91, and of reintervention-free survival was 0.44. Older age at the angioplasty was associated with a higher incidence of reinterventions (hazard ratio 1.057; 95% confidence interval 1.012-1.103; P = 0.010). The type of surgery and the recoarctation anatomy did not influence the outcome. In 69 patients aneurysm formation was studied by high-sensitive methods with only one positive finding per 462 patient-years. CONCLUSION: Angioplasty is safe and effective regardless of the type of surgery used and the recoarctation anatomy. Older age at the angioplasty is associated with a higher incidence of reinterventions.
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Reich et al. (2008) conducted a cohort in Recurrent aortic coarctation (n=99). Percutaneous balloon angioplasty was evaluated on Incidence of reinterventions (associated with older age at angioplasty) (HR 1.057, 95% CI 1.012-1.103, p=0.010). Percutaneous balloon angioplasty for recurrent aortic coarctation yielded a 20.7-year survival probability of 0.91, with older age increasing reintervention risk (HR 1.057; 95% CI 1.012-1.103).
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