Key result
Balloon angioplasty for discrete aortic coarctation is linked to an ~83% drop in mean systolic gradient.
Why the study?
Long-term outcomes after percutaneous balloon angioplasty for discrete coarctation of the aorta have not been fully characterized.
Does percutaneous balloon angioplasty reduce systolic gradient in patients with discrete coarctation of the aorta?
Cohort (n=110)
Does percutaneous balloon angioplasty reduce systolic gradient in patients with discrete coarctation of the aorta?
Absolute Event Rate: 8% vs 48%
p-value: p=<0.0001
Percutaneous balloon angioplasty effectively reduces systolic gradients in patients with discrete coarctation of the aorta, with good long-term results particularly in patients over 3 months of age.
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May support balloon angioplasty for gradient relief in discrete coarctation; leaves open randomized comparisons to surgery.
Zuhdi Lababidi (1992) conducted a cohort in Discrete coarctation of the aorta (n=110). Percutaneous balloon coarctation angioplasty vs. Pre-angioplasty baseline was evaluated on Mean systolic gradient (p=<0.0001). Percutaneous balloon angioplasty for discrete coarctation of the aorta significantly decreased the mean systolic gradient from 48 to 8 mmHg (P<0.0001).
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