In Indian patients surviving an anterior wall myocardial infarction, the incidence of LV thrombus is 6.5%, and it is predicted by echocardiographic parameters and mean platelet volume.
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Incidence estimates in Indian AWMI patients are hypothesis-generating; larger trials needed before guiding anticoagulation.
BACKGROUND prospectively estimate the incidence of left ventricular (LV) thrombus over one-year follow-up in patients presenting with wall myocardial infarction (AWMI) and to identify the predictors of LV thrombus, to study the course of LV thrombus clinically evident thrombo-embolic manifestations over a one-year period in Indian population. hundred patients with first AWMI were prospectively and consecutively enrolled. At the time of hospitalization, key and clinical characteristics were collected along with echocardiographic data. Patients were followed up for or change in existing LV thrombus and thromboembolic event. of LV thrombus was 6.5%. The mean platelet volume and LV wall motion score index (LVWMSI) were significantly in LV thrombus patients in comparison to non-LV thrombus patients. Baseline ejection fraction (EF), mean mitral E wave time (MDT) and mean mitral propagation velocity (MVP) were significantly lower in LV thrombus patients. At oneyear follow-up, 30.76% patients showed disappearance of thrombus, 46.15% showed decrease in size and 23.07% showed no in size while 15.38% patients showed embolic events. MPV at admission, low baseline EF, high LVWMSI, low baseline MDT and low MVP are independent predictors of LV . Moreover, patients undergoing primary PTCA have decreased risk of LV thrombus.
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Govindan et al. (2019) studied this question.
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