Pericardial effusion can be a prominent manifestation of systemic lupus erythematosus, and awareness is crucial to avoid misdiagnosis.
Alerts clinicians to consider SLE in unexplained pericardial effusion to avert misdiagnosis; case reports leave open prevalence and education impact.
Four cases of systemic lupus erythematosus with pericardial effusion as a prominent manifestation are reported. Lack of awareness of this finding as a not infrequent part of the disease entity led to misdiagnosis in 2 instances and incorrect treatment in 1. The literature on the subject is reviewed and suggestions are offered for diagnosis.
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Stanley S. Bergen (1960) studied this question.
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