Why the study?
Do procainamide and N-acetylprocainamide alter electrophysiological properties and terminate atrial flutter in a canine model?
Population
12 instrumented conscious dogs with atrial flutter resulting from circus movement around the tricuspid…
Design
Preclinical
Authors
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Should not change clinical practice; leaves open differential electrophysiological effects of procainamide versus NAPA in atrial flutter.
Do procainamide and N-acetylprocainamide alter electrophysiological properties and terminate atrial flutter in a canine model?
Procainamide and NAPA exhibit different electrophysiological effects on transmembrane potentials despite both showing efficacy in terminating atrial flutter in a canine model.
Wu et al. (1987) studied this question.
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