Why the study?
Immune checkpoint inhibitor-related myocarditis is rare but life-threatening, warranting better clinical and prognostic characterization.
What are the prognostic features and clinical outcomes of immune checkpoint inhibitor-induced myocarditis?
Design
Multicenter cross-sectional retrospective study
Authors
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Lower mortality than prior reports in ICI-myocarditis; leaves open validation of prognostic factors like troponin and autoimmunity.
What are the prognostic features and clinical outcomes of immune checkpoint inhibitor-induced myocarditis?
ICI-induced myocarditis is a severe complication with high mortality, and severe cases are strongly associated with pre-existing autoimmune disease, markedly elevated troponin, and anti-acetylcholine receptor autoantibodies.
Coustal et al. (2023) studied this question.
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