January 1, 2000Journal of Cardiovascular Pharmacology
How Can Hypertensive Patients Be Better Treated? The Contribution of Combination Therapy
Structured PICO
P
Population
145,000 subjects examined at the Centre d'Investigations Préventives et Cliniques in Paris (IPC), focusing on patients with high blood pressure.
I
Intervention
Antihypertensive treatment, including combination therapy (specifically mentioning trandolapril-verapamil fixed combination)
O
Outcome
Blood pressure control (systolic blood pressure <140 mmHg and diastolic blood pressure <90 mmHg)surrogate
A large French population study reveals poor hypertension control rates, with only 20% of hypertensive patients treated and less than 27% of those treated achieving target blood pressure, highlighting the need for combination therapy.
Authors
Discussion
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Implication
Documents low hypertension treatment and control rates; hypothesis-generating for strategies to improve real-world management.
Cite This Study
Bénétos et al. (2000) studied this question.