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May 1, 1973BloodOpen Access

Ristocetin: A Means of Differentiating Von Willebrand’s Disease Into Two Groups

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Why the study?

Does ristocetin differentiate von Willebrand's disease into two groups based on platelet aggregation?

Population

Patients with von Willebrand's disease

Design

Other

Authors

MHMargaret A. HowardThe Royal Melbourne HospitalRSR. J. SawersThe Alfred HospitalBFB. G. FirkinThe University of Sydney

Discussion

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Implication

Ristocetin response may distinguish vWD subgroups; leaves open diagnostic utility pending prospective validation.

Structured PICO

Does ristocetin differentiate von Willebrand's disease into two groups based on platelet aggregation?

P
Population
Patients with von Willebrand's disease
I
Intervention
Ristocetin
O
Outcome
Platelet aggregationsurrogate

Ristocetin can be used to differentiate von Willebrand's disease into two groups based on platelet aggregation response.

Cite This Study

Howard et al. (1973) studied this question.

synapsesocial.com/papers/6a710582e71d69abee08fedahttps://doi.org/10.1182/blood.v41.5.687.687
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet Adhesiveness in von Willebrand’s Disease1969 · 190 citations
  2. 2Qualitative Platelet Defects with Reduced Life-Span in Acute Leukaemia*1972 · 15 citations
  3. 3Platelet Defect of Infectious Mononucleosis1971 · 23 citations
  4. 4Platelet Adhesiveness in Von Willebrand's Disease: A Study with a New Modification of the Glass Bead Filter Method1970 · 141 citations