Why the study?
Does supervised exercise improve HDL subfractions, cholesterol efflux capacity, and inflammatory markers in patients with peripheral artery disease?
Does supervised exercise improve HDL subfractions, cholesterol efflux capacity, and inflammatory markers in patients with peripheral artery disease?
Supervised exercise does not significantly alter HDL subfractions, cholesterol efflux capacity, or inflammatory markers at 6 months in patients with PAD, though baseline inflammation is inversely associated with HDL function.
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HDL-inflammation associations in PAD are hypothesis-generating; leaves open whether supervised exercise modifies HDL function to affect clinical outcomes.
Albaghdadi et al. (2017) studied this question.
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