Population
Smooth muscle cells from the human aorta
Comparison
2-decenoic acid (DA) vs Control conditions (absence of DA)
Design
Preclinical
Authors
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May modulate vascular smooth muscle in animal models; leaves open human translation or therapeutic relevance.
2-decenoic acid increases the open probability of Ca2+-activated potassium channels in human aortic smooth muscle cells, possibly due to membrane fluidization.
Bregestovski et al. (1989) studied this question.
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