Population
Calcium-activated potassium channels from cultured rat skeletal muscle studied in excised patches
Comparison
N-bromoacetamide (NBA) (0.3-1 mM) vs Untreated channels and untreated channels in…
Design
Preclinical
Authors
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NBA selectively disrupts Ca2+-dependent gating in BK channels; hypothesis-generating for cardiovascular ion channel studies but leaves clinical translation open.
NBA removes a calcium-dependent component of channel opening in calcium-activated potassium channels from rat skeletal muscle.
B S Pallotta (1985) studied this question.
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