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September 1, 2003Journal of Applied Physiology

Neurohumoral responses during prolonged exercise in humans

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Why the study?

Does prolonged exercise with hyperthermia alter cerebral oxygen-to-carbohydrate uptake ratio, dopamine, or tryptophan balances compared to exercise without hyperthermia in endurance-trained subjects?

Population

8 endurance-trained subjects

Comparison

Prolonged exercise with hyperthermia vs Prolonged exercise without hyperthermia

Design

RCT, randomized

Follow-up

during exercise and recovery

Authors

LNLars NyboUniversity of CopenhagenBNBodil NielsenUniversity of CopenhagenEBEva BlomstrandKarolinska Institutet

Discussion

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Overview

Hyperthermic exercise increases cerebral carbohydrate demand during recovery; extends evidence on brain substrate metabolism in endurance athletes.

Structured PICO

Does prolonged exercise with hyperthermia alter cerebral oxygen-to-carbohydrate uptake ratio, dopamine, or tryptophan balances compared to exercise without hyperthermia in endurance-trained subjects?

P
Population
8 endurance-trained subjects
I
Intervention
Prolonged exercise with hyperthermia
C
Comparator
Prolonged exercise without hyperthermia (control trial)
O
Outcome
Cerebral oxygen-to-carbohydrate uptake ratio (O2/CHO), cerebral balances of dopamine, and tryptophansurrogate

The brain has an increased need for carbohydrates during recovery from strenuous exercise with hyperthermia, but enhanced perception of effort is not related to cerebral dopamine or tryptophan balances.

Cite This Study

Nybo et al. (2003) studied this question.

synapsesocial.com/papers/6a7119f8a7fbea1e44084ebbhttps://doi.org/10.1152/japplphysiol.00241.2003
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