Why the study?
The pseudocavitation sign had not been described in previous COVID-19 studies, despite detailed descriptions of other computed tomography imaging features.
The 'vacuolar sign' described in COVID-19 pneumonia may actually represent pseudocavitation due to pre-existing cystic changes rather than a novel disease-specific sign.
Pseudocavitation in COVID-19 may reflect pre-existing changes; leaves open its specificity as a diagnostic sign.
Coronavirus disease 2019 (COVID-19) pneumonia computed tomography imaging features have been described in detail in many studies. The pseudocavitation sign has not been described in the previous COVID-19 studies. We present chest computed tomography scans of 5 reverse transcriptase-polymerase chain reaction positive patients with COVID-19 pneumonia who has bare areas among pulmonary infiltrates. All 5 also had previous scans with similarly sized low attenuated areas in the same location prior to the addition of pulmonary infiltrates. The pre-existing cystic changes had become remarkable due to the contrast around them after the pulmonary infiltrates added. Therefore, they should be termed as "pseodocavity" according to Fleischner Society glossary. Small air-containing spaces between pulmonary infiltrates have been termed in previous COVID-19 studies as a new sign called "round cystic changes/air bubble sign/vacuolar sign." We would like to draw attention that the vacuolar sign and the synonyms may be the pseudocavity sign that is due to pre-existing changes rather than a new defined sign.
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Gürdal et al. (2021) studied this question.
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