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A glaucoma-like rise in intraocular pressure following prolonged use of cortisone was documented by Francois in 1954. Since then, the in- fluence of glucocorticosteroid (steroid) eye drops on intraocular pressure has been studied extensively. Provocative testing of healthy eyes with topical steroid preparations has led to the characterization of a 'steroid response' consisting of a gradual rise in intraocular pressure when medication is instilled several times daily over a period of 4 to 6 weeks. When the topical steroid is discontinued the intra- ocular pressure returns to normal levels.
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Schwartz et al. (1972) studied this question.
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