Why the study?
Does antiarrhythmic drug therapy reduce the rate of sudden death in patients with asymptomatic or mildly symptomatic ventricular ectopic activity after myocardial infarction?
Population
Patients with asymptomatic or mildly symptomatic ventricular ectopic activity after myocardial infarction
Comparison
Antiarrhythmic drug therapy vs Placebo
Design
Editorial, placebo-controlled
Follow-up
long-term
Authors
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Prompts caution against routine ectopy suppression post-MI; leaves open optimal strategies for sudden-death prevention.
Does antiarrhythmic drug therapy reduce the rate of sudden death in patients with asymptomatic or mildly symptomatic ventricular ectopic activity after myocardial infarction?
The preliminary results of CAST challenge conventional wisdom regarding the suppression of ventricular ectopic activity post-myocardial infarction.
Jeremy N. Ruskin (1989) studied this question.
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