Challenges in the treatment of hypertriglyceridemia: glass half empty or half full?
Population
Patients with hypertriglyceridemia
Design
Review
Authors
Discussion
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Member takes
Implication
Lifestyle measures remain first-line for hypertriglyceridemia; review leaves open net benefit of adding fibrates or omega-3.
Structured PICO
P
Population
Patients with hypertriglyceridemia
I
Intervention
Non-statin agents (fibrates and n-3 polyunsaturated fatty acids) added to statins
The clinical use of non-statin agents in hypertriglyceridemia requires a careful trade-off between anticipated benefits and potential adverse events, though fenofibrate may be considered in high-risk patients with persistent triglyceride elevation.
Cite This Study
Sahebkar et al. (2015) studied this question.