Key Points
- Examine the delivery gaps, hospital capability constraints, and time delays associated with providing primary percutaneous coronary intervention for ST-elevation myocardial infarction.
- Reviewed clinical trial evidence evaluating primary percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction management.
- Assessed national health system data across approximately 5000 acute-care hospitals in the United States regarding catheterization capabilities and guideline adherence for reperfusion timing.
- Approximately one third of STEMI patients receive no reperfusion therapy despite eligibility, and only 18% receive primary percutaneous coronary intervention.
- Fewer than 40% of patients treated with primary percutaneous coronary intervention achieve reperfusion within the guideline-recommended 90-minute door-to-balloon window.
- Only approximately 1200 of nearly 5000 acute-care hospitals possess percutaneous coronary intervention capabilities, necessitating regional transfer and triage protocols.
Structured PICO
PPopulationPatients with ST-segment elevation myocardial infarction (STEMI) in the United States
IInterventionPrimary percutaneous coronary intervention (PCI) and regionalized care protocols
Despite evidence supporting primary PCI for STEMI, significant gaps remain in its timely delivery and utilization in the United States, highlighting the need for regionalized care systems.