Lawrence Livermore National Laboratory`s PEREGRINE project

PEREGRINE is an all-particle, first-principles 3D Monte Carlo dose calculation system designed to serve as a dose calculation engine for clinical radiation therapy treatment planning (RTP) systems. By taking advantage of recent advances in low cost computer commodity hardware, modern symmetric multiprocessor architectures and state-of- the-art Monte Carlo transport algorithms., PEREGRINE performs high resolution, high accuracy, Monte Carlo RTP calculation in times that are reasonable for clinical use. Because of its speed and simple interface with conventional treatment planning systems, PEREGRINE brings Monte Carlo radiation transport calculations to the clinical RTP desktop environment. Although PEREGRINE is designed to calculate doe distributions for photon, electron, fast neutron and proton therapy, this paper focuses on photon teletherapy.