What question did this study set out to answer?

Identify clinical, physical, and laboratory features that facilitate the accurate preoperative diagnosis of atrial myxoma and assess long-term surgical outcomes.

November 4, 1974JAMA

The Clinical Syndrome of Atrial Myxoma

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Why the study?

What are the clinical features that facilitate the correct diagnosis of atrial myxoma, and what are the long-term outcomes after surgical resection?

Population

17 patients with atrial myxoma

Design

Case_series

Follow-up

Up to 15 years

Authors

MPMichael Peters

Discussion

Member takes

Overview

Supports triad recognition for atrial myxoma diagnosis; leaves open generalizability of recurrence-free outcomes beyond small series.

Key Points

Identify clinical, physical, and laboratory features that facilitate the accurate preoperative diagnosis of atrial myxoma and assess long-term surgical outcomes.
Retrospective review of clinical records for 17 patients with atrial myxoma evaluated and treated at a single institution.
Evaluation of clinical course, auscultatory signs, laboratory parameters including sedimentation rate and immunoglobulin levels, angiographic findings, and postoperative follow-up up to 15 years.
All 17 patients presented with features of the classic triad of obstructive, constitutional, and embolic effects, with 10 exhibiting symptoms for two years or less and 9 experiencing syncope or dizziness.
Auscultation mimicked rheumatic mitral valve disease, but distinguishing features included variable auscultatory findings in 5 patients, accentuated first heart sound or opening snap with mitral regurgitation in 4, and systemic inflammatory laboratory abnormalities in 10.
Preoperative diagnosis was verified by angiography, and definitive surgical resection achieved zero tumor recurrences across follow-up intervals extending up to 15 years.

Structured PICO

What are the clinical features that facilitate the correct diagnosis of atrial myxoma, and what are the long-term outcomes after surgical resection?

Population

17 patients with atrial myxoma

Intervention

Definitive tumor resection

Outcome

Clinical features facilitating correct diagnosis and long-term tumor recurrence

Atrial myxoma presents with a classic triad of obstructive, constitutional, and embolic effects, and definitive surgical resection yields excellent long-term outcomes without recurrence.

Cite This Study

Michael Peters (1974) studied this question.

synapsesocial.com/papers/6a7120796c240de38cdc0af5 https://doi.org/10.1001/jama.1974.03240050023018

View Full Paper

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November 4, 1974JAMA

The Clinical Syndrome of Atrial Myxoma

View Full Paper

Ask AI

Bookmark

Why the study?

What are the clinical features that facilitate the correct diagnosis of atrial myxoma, and what are the long-term outcomes after surgical resection?

Population

17 patients with atrial myxoma

Design

Case_series

Follow-up

Up to 15 years

Authors

MPMichael Peters

Discussion

Member takes

Overview

Supports triad recognition for atrial myxoma diagnosis; leaves open generalizability of recurrence-free outcomes beyond small series.

Key Points

Identify clinical, physical, and laboratory features that facilitate the accurate preoperative diagnosis of atrial myxoma and assess long-term surgical outcomes.
Retrospective review of clinical records for 17 patients with atrial myxoma evaluated and treated at a single institution.
Evaluation of clinical course, auscultatory signs, laboratory parameters including sedimentation rate and immunoglobulin levels, angiographic findings, and postoperative follow-up up to 15 years.
All 17 patients presented with features of the classic triad of obstructive, constitutional, and embolic effects, with 10 exhibiting symptoms for two years or less and 9 experiencing syncope or dizziness.
Auscultation mimicked rheumatic mitral valve disease, but distinguishing features included variable auscultatory findings in 5 patients, accentuated first heart sound or opening snap with mitral regurgitation in 4, and systemic inflammatory laboratory abnormalities in 10.
Preoperative diagnosis was verified by angiography, and definitive surgical resection achieved zero tumor recurrences across follow-up intervals extending up to 15 years.

Structured PICO

What are the clinical features that facilitate the correct diagnosis of atrial myxoma, and what are the long-term outcomes after surgical resection?

Population

17 patients with atrial myxoma

Intervention

Definitive tumor resection

Outcome

Clinical features facilitating correct diagnosis and long-term tumor recurrence

Atrial myxoma presents with a classic triad of obstructive, constitutional, and embolic effects, and definitive surgical resection yields excellent long-term outcomes without recurrence.

Cite This Study

Michael Peters (1974) studied this question.

synapsesocial.com/papers/6a7120796c240de38cdc0af5 https://doi.org/10.1001/jama.1974.03240050023018

Also Consider

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