Population
2 patients with myxoma of the left atrium
Design
Case_series
Authors
Discussion
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Member takes
Implication
May aid preoperative myxoma recognition; leaves open generalizability from single case.
Key Points
- To correlate intracardiac heart sounds and pressure waveforms with the physical movement of left atrial myxomas across the mitral valve.
- Evaluated two patients (N=2) with left atrial myxoma using left heart catheterization and synchronized electrocardiographic cineangiography.
- Correlated intracardiac pressure tracings and phonocardiographic sounds with tumor movement, with findings subsequently confirmed during surgical operation.
- During early systole, sudden tumor transit from the left ventricle into the left atrium produced a notch in rising ventricular pressure, an exaggerated atrial c wave, and loud, late components of the first heart sound.
- During early diastole, rapid tumor transit across the mitral valve caused an abrupt decline in left atrial volume and a rapid y descent despite severe valve obstruction, terminating in an early diastolic 'tumor plop' sound as movement halted in the ventricle.
Structured PICO
P
Population
2 patients with myxoma of the left atrium
I
Intervention
Left heart catheterization and cineangiography
O
Outcome
Correlation of heart sounds and pressure waves with movement of the tumorsurrogate
Left atrial myxomas produce characteristic hemodynamic and auscultatory findings, such as a rapid y descent and a 'tumor plop', which can aid in preoperative diagnosis.
Cite This Study
Pitt et al. (1967) studied this question.