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Histological examination of 42 early lesions of molluscum contagiosum was performed. At the top of the molluscum papule, the epidermis cylindrically hung down into the dermis, thus forming an epidermal cylinder with a narrow canal. Acanthomatous change occurred at the bottom of the epidermal cylinder. Thirteen of the 42 molluscum lesions showed a direct connection with components of hair follicle. It is suggested that the central pitting of molluscum contagiosum may be the ostium of pilar infundibulum.
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Uehara et al. (1980) studied this question.
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