Why the study?
Does obesity reduce adipose tissue oxygenation and drive inflammation in humans?
Population
21 men and women (9 lean and 12 overweight/obese)
Design
Cross-sectional
Authors
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Adipose hypoxia associated with obesity; hypothesis-generating for inflammation-driven metabolic dysfunction, needs prospective confirmation.
Does obesity reduce adipose tissue oxygenation and drive inflammation in humans?
Adipose tissue rarefaction and lower oxygenation in obesity may drive adipose tissue inflammation, suggesting a mechanism for obesity-related metabolic dysfunction.
Pasarica et al. (2008) studied this question.
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