Why the study?
Does 2-dimensional strain and strain rate imaging differentiate between hypertrophic cardiomyopathy and physiological hypertrophy in athletes?
Does 2-dimensional strain and strain rate imaging differentiate between hypertrophic cardiomyopathy and physiological hypertrophy in athletes?
Comparative study reveals distinct myocardial deformation patterns in hypertrophic cardiomyopathy versus athlete's heart, highlighting strain imaging for differential diagnosis.
Background: In young competitive athletes, the differential diagnosis between nonpathological changes in cardiac morphology associated with training (commonly referred to as “athlete's heart”) and certain cardiac diseases with potential for sudden death as hypertrophic cardiomyopathy (HCM), is an important and not uncommon clinical problem. Objective: This study was designed to characterize global & regional myocardial deformation using 2-dimensional strain & strain rate (SR) imaging in HCM & compare it to physiological hypertrophy in athletes. Methods: The study comprised 22 patients with HCM. 81% had asymmetric septal hypertrophy, 34 athletes with septal thickness >12 mm & 28 age matched healthy subjects as a control group. Apical four chamber view was displayed; speckle tracking was used to measure longitudinal peak systolic strain (εsys), peak systolic strain rate (SRsys), time to peak (ε) [TTP], post systolic strain (εPSS) and intra-ventricular systolic delay (intra-V delay). These parameters were quantified in basal, mid & apical segments of septal & lateral walls of the left ventricle.
No takes yet. Share an insight, caveat, or question.
Elnoamany et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: